1. Universidade Federal da Bahia
  2. Instituto de Ciências da Saúde (ICS)
  3. Programa de Pós-Graduação em Processos Interativos dos Órgãos e Sistemas (PPGPIOS)
  4. Dissertação (PPGPIOS)
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dc.creatorNeiva, Naiara Brunelle Oliveira-
dc.date.accessioned2024-01-12T13:07:39Z-
dc.date.available2024-01-12T13:07:39Z-
dc.date.issued2023-09-29-
dc.identifier.citationNEIVA, Naiara Brunelle Oliveira. Qualidade e duração do sono e a síndrome metabólica: um estudo de associação. 2023. 78 f. Dissertação (Mestrado Acadêmico em Processos Interativos de Órgãos e Sistemas) - Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, 2023.pt_BR
dc.identifier.urihttps://repositorio.ufba.br/handle/ri/38862-
dc.description.abstractINTRODUCTION: Metabolic Syndrome (MS) is a complex disorder, characterized by cardiovascular risk factors, related to the simultaneous impairment of metabolic and vascular functions and central obesity. However, other mechanisms appear to be related to MS, such as sleep disorders, which appear to interrupt essential homeostatic processes. Therefore, this study aims to investigate the association between sleep quality and MS and its associated factors. METHODS: this is a cross-sectional study, with 166 adult and elderly individuals, of both sexes, attended at the Center for Research and Extension in Nutritional Genomics and Metabolic Dysfunctions (GENUT/UNEB). The diagnosis of MS was defined according to criteria proposed by the International Diabetes Federation (IDF, 2006) and the qualitative and quantitative assessment of sleep, based on the application of the Pittsburgh Sleep Quality Index (PSQI). Sleep duration was categorized as: short, <6 hours per night; adequate, 6-8 hours per night and long, >8 hours per night. Data were analyzed using Stata software (version 12.0). The Chi-Square test or Fisher's exact test were used to identify associations between nominal variables, and the Student's t-test, Mann-Whitney or Kruskal-Wallis test for quantitative variables. To evaluate the correlation coefficient between non-parametric variables, Spearman's coefficient was applied. The significance level established was 5%. This project was approved by the UNEB Research Ethics committee, CAEE: 03409712.9.3001.5023. RESULTS: Data from 166 individuals were investigated, 116 with MS and 50 without MS. No association was found between sleep quality (p=0.357) and duration (p=0.159) and MS. However, in alcoholic individuals, there was an association between poor sleep quality and low HDL-c (p= 0.005) and between adequate sleep duration and hypertriglyceridemia (p=0.045). A moderate, inverse and statistically significant relationship was also observed between sleep duration and quality (p= 0.000). Furthermore, a 63% lower chance of alcoholics having MS was observed, compared to non-drinkers. Age was considered a risk factor for MS and white skin color/race was a protective factor. The majority of participants reported adequate sleep duration (62.05%), which can be explained by the sociodemographic characteristics of the studied population. CONCLUSION: In this study, no association was found between sleep quality and duration with MS, which can be explained by the heterogeneity of the types of study, the populations studied, the MS classification criteria and the collection of sleep data. The results obtained reinforce the relevance of alcoholism as a modifying factor in this relationship. Additional studies are needed to investigate the role of sleep in MS, and above all, the dose-response effect of alcohol consumption on sleep.pt_BR
dc.languageporpt_BR
dc.publisherUNIVERSIDADE FEDERAL DA BAHIApt_BR
dc.subjectSonopt_BR
dc.subjectQualidade do sonopt_BR
dc.subjectDuração do sonopt_BR
dc.subjectSíndrome metabólicapt_BR
dc.subject.otherSleeppt_BR
dc.subject.otherSleep qualitypt_BR
dc.subject.otherSleep durationpt_BR
dc.subject.otherMetabolic Syndromept_BR
dc.titleQualidade e duração do sono e a síndrome metabólica: um estudo de associaçãopt_BR
dc.title.alternativeSleep quality and duration and metabolic syndrome: an association studypt_BR
dc.typeDissertaçãopt_BR
dc.publisher.programPrograma de Pós-Graduação em Processos Interativos dos Órgãos e Sistemas (PPGORGSISTEM) pt_BR
dc.publisher.initialsUFBApt_BR
dc.publisher.countryBrasilpt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDEpt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDE::NUTRICAOpt_BR
dc.contributor.advisor1Araújo, Edilene Maria Queiroz-
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/7394280781506129pt_BR
dc.contributor.advisor-co1Santos, Luama Araújo dos-
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/9350244242655214pt_BR
dc.contributor.referee1Araújo, Edilene Maria Queiroz-
dc.contributor.referee1Latteshttp://lattes.cnpq.br/7394280781506129pt_BR
dc.contributor.referee2Vázquez, Mírian Rocha-
dc.contributor.referee2Latteshttp://lattes.cnpq.br/0802126145296730pt_BR
dc.contributor.referee3Carvalho, Fernando Luís de Queiroz-
dc.contributor.referee3Latteshttp://lattes.cnpq.br/6679400555126839pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/6769309123195074pt_BR
dc.description.resumoINTRODUÇÃO: A Síndrome Metabólica é uma desordem complexa, caracterizada por fatores de risco cardiovascular, relacionados ao comprometimento simultâneo de funções metabólicas, vasculares e obesidade central. Contudo, outros mecanismos parecem estar relacionados a essa síndrome, como os distúrbios de sono, que parecem interromper processos homeostáticos essenciais. Assim, este estudo tem por objetivo investigar a associação entre a qualidade do sono e a Síndrome Metabólica e seus fatores associados. MÉTODOS: Trata-se de um estudo do tipo transversal, com 166 indivíduos adultos e idosos, de ambos os sexos, atendidos no Núcleo de Pesquisa e Extensão em Genômica Nutricional e Disfunções Metabólicas, da Universidade do Estado da Bahia. O diagnóstico foi definido de acordo com critérios propostos pela Federação Internacional de Diabetes, e a avaliação quali-quantitativa do sono, a partir da aplicação do Índice de Qualidade do Sono de Pitsburgh. A duração do sono foi categorizada em curta, <6 horas por noite; adequada,6-8 horas por noite e longa, >8 horas por noite, sendo os dados analisados pelo software Stata (versão 12.0). Utilizaram-se o teste Qui-Quadrado ou o Exato de Fisher, para identificar associações entre as variáveis nominais, e o teste t de Student, Mann-Whitney ou Kruskal-Wallis, para as variáveis quantitativas. Visando avaliar o coeficiente de correlação entre variáveis não paramétricas, aplicou-se o coeficiente de Spearman. O nível de significância estabelecido foi de 5%. RESULTADOS: Investigaram-se dados de 166 indivíduos, sendo 116 com a síndrome e 50 sem ela. Não foi encontrada associação entre qualidade (p=0,357) e duração (p=0,159) do sono e a Síndrome Metabólica. Entretanto, em indivíduos etilistas, houve associação entre má qualidade do sono e baixo HDL-c (p= 0,005) e entre duração adequada de sono e hipertrigliceridemia (p=0,045). Também observou-se relação moderada, inversa e estatisticamente significativa entre duração e qualidade do sono (p= 0,000). Ademais, concluiu-se por uma chance 63% menor de etilistas apresentarem Síndrome Metabólica, em comparação a não consumistas. A idade foi considerada fator de risco para a referida síndrome e a cor/raça de pele branca, fator protetor. A maioria dos participantes relatou duração adequada de sono (62,05%), o que pode ser explicado pelas características sociodemográficas da população estudada. CONCLUSÃO: Neste estudo, não foi encontrada associação entre qualidade e duração do sono com a Síndrome Metabólica, o que pode ser explicado pela heterogeneidade dos tipos de estudo, das populações estudadas, dos critérios de classificação da síndrome e da obtenção dos dados de sono. Os resultados obtidos reforçam a relevância do etilismo como fator modificador dessa relação. Estudos adicionais são necessários para investigar o papel do sono na referida comorbidade e, sobretudo, o efeito dose-resposta do consumo alcoólico no sono.pt_BR
dc.publisher.departmentInstituto de Ciências da Saúde - ICSpt_BR
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